These two open source scripts are very useful when combined with cron:

s3 Tools : http://sourceforge.net/projects/s3tools/

OpenSource tools to access Amazon S3 file storage. s3cmd – unix-like tools to manipulate stored files from the command line, s3fuse – driver to mount the S3 storage locally.

and

automysqlbackup : http://sourceforge.net/projects/automysqlbackup/

A script to take daily, weekly and monthly backups of your MySQL databases using mysqldump. Features – Backup mutiple databases – Single backup file or to a seperate file for each DB – Compress backup files – Backup remote servers